Oligonucleotides are short single-stranded sections of DNA orRNA that contain 20-deoxyribo-nucleosides or ribo-nucleosides,respectively, which are linked by 30–50phosphodiester linkages(Fig.1a). Antisense oligonucleotides are those that are complemen-tary to a section of naturally occurring RNA, such as an mRNA or aviral RNA, to form Watson–Crick base pairs and to thus inhibit abiological f…
Sex is at the core of our identities. And when it becomes a compulsion, it can unravel our lives. Out of the Shadows is the premier work on this disorder, written by a pioneer in its treatment. Revised and updated to include the latest research--and to address the exploding phenomenon of cybersex addiction--this third edition identifies the danger signs, explains the dynamics, and describes the…
Climate change is one of the most serious problems facing the agriculture today. In a many countries, drought in conjunction with high temperature becomes a significant risk for sustainable agricultural production. In general, drought stress limits productivity of major crops by inducing different morphological, physiological and molecular changes in plants (Ashraf et al. 201…
The road’s potholes were a stark contrast to the destination of the coach-loadof young women driving over them: a brand new building housing one ofBangalore’s many internet-enabled service companies—this one providingaccountancy support services—newly built on the outskirts of the city. Thiscontrast is not something we saw only in India. In the overcrowded streets ofIndonesia’s capita…
This chapter briefly describes the goal and general argument of the book, along with its theoretical framework and data collection, and introduces the Swedish case. First, we set the discussion of labour movements’ trade union revitalization and usage of social media—and particularly of YouTube—into the broader context of scholarly liter-at…
The agent is the one that does things. There somehow in the midst of all the things that cause the agent to move, you find an agent in turn causing things. You find action. The agent displays activity.Those things that are not agents do nothing. There in the midst of all the things that cause them to move and that they in turn cause, you find . . . mere happenings, nothing else…
Over de eerste eeuwen van het christendom in het noorden van de Lage Landen valt weinig met zekerheid te zeggen. De schoolboekjes van vroeger wilden de mensen nog wel doen geloven dat met de komst van missionarissen als Willibrord en Bonifatius de verspreiding van het christendom op Nederlandse bodem een beklonken zaak was. Maar historici vermoeden inmiddels dat …
Planetary scientists suspect that, when young, our planet met with an enormouscelestial body in a random collision that tilted the earth’s rotational axis relativeto its orbital plane around the sun. This tilt has since determined which parts ofour globe are most exposed to solar radiation at different points in its solar cir-cuit, as a key physical pattern dictating the annual cycles of life…
When using the terms mice and rats, we usually mean small ani-mals with a long scaly tail. These names are applied mainly to rodents, but not exclusively. In various languages, shrews are also called mice (e.g. German Spitzmäuse), as are bats and some marsu-pials (marsupial mice). Even one carnivore, the Egyptian mongoose (Herpestes ichneumon), is also called Waoh’s rat. First of all, it wou…
Di hari pertamanya bekerja sebagai reporter majalah berita, Wikan Larasati - yang baru lulus kuliah dengan cemerlang - merasa diremehkan kantornya karena ditugaskan meliput peluncuran album diva pop yang seksi, Melanie Capricia - populer dengan panggilan MC. Namun keengganan Wikan dengan cepat berubah menjadi antusiasme yang berkobar setelah tersiar kabar tewasnya pengacara muda kondang, Rangga…
Telling the story of Old Sarum and Salisbury, from the mid-10th century to the start of the 20th, this book brings together the most up-to-date thinking on the archaeological evidence, and, through analysis of the rich documentary record, provides a fresh take on the story of this most illustrious cathedral city in the heart of southern England. Tales of Two Cities tells the story of Old Sar…
This e-book explores some of the contributions of psychology to yesterday’s great space race, today’s orbiter and International Space Station missions, and tomorrow’s journeys beyond Earth’s orbit. Early missions into space were typically brief, and crews were small, often drawn from a single nation. As an intensely competitive space race has given way to international cooperation over …
In the final volume of the series, Chertok recounts the period of 1968 to 1974. Much has been written in the West on the history of the Soviet space program but few Westerners have read direct first-hand accounts of the men and women who were behind the many Russian accomplishments in exploring space. The memoirs of Academician Boris Chertok, translated from the original Russian, fills that ga…
In this third volume Chertok continues his fascinating narrative on the early history of the Soviet space program, from 1961 to 1967, arguably the peak of the effort. Much has been written in the West on the history of the Soviet space program but few Westerners have read direct first-hand accounts of the men and women who were behind the many Russian accomplishments in exploring space. The …
Much has been written in the West on the history of the Soviet space program but few Westerners have read direct first-hand accounts of the men and women who were behind the many Russian accomplishments in exploring space. The memoirs of Academician Boris Chertok, translated from the original Russian, fills that gap. In these writings, spread over four volumes, Chertok not only describes and re…
August Strindberg (1849–1912) was an extraordinarily prolific writer whose col-lected works encompass no fewer than 72 volumes of drama, prose and poetry as well as 22 volumes of letters.1 In this extensive literary production, The Occult Diary occupies a unique and central position. Strindberg kept the diary from February 1896, when he moved into the Hotel Orfila in Paris, until the sum…
Much has been written in the West on the history of the Soviet space program but few Westerners have read direct first-hand accounts of the men and women who were behind the many Russian accomplishments in exploring space. The memoirs of Academician Boris Chertok, translated from the original Russian, fills that gap. In these writings, spread over four volumes, Chertok not only describes and re…
Darren Anderton played 30 times for the England men’s national football team and made 299 Premier League appearances for Tottenham Hotspur. To fans of a certain age, he is known by another name: ‘Sicknote’. ‘I had a migraine and was throwing up before a Portsmouth game’, recounted Anderton in 2016, some eight years after his final Football League match…
This open access edited volume reports on a unique network of innovative in-school and out-of-school programs, University-Community Links. UC Links connects university faculty and students with young people and their families in diverse communities around the world. Chapters in this volume describe programs in the United States (California) as well as Germany, Italy, Spain, Uganda, and Uruguay.…
Communities great and small across Europe for eight centuries have contracted with doctors. Physicians provided citizen care, helped govern, and often led in public life. Civic Medicine stakes out this timely subject by focusing on its golden age, when cities rivaled territorial states in local and global Europe and when civic doctors were central to the rise of shared, organized written inform…
In the beginning, when the world was just fifty centim-eters long, there was Jeanne’s inquiring face. A five-year-old face, flush up against the months-old fragment I then was, my opaque little mole eyes fumbling across this earliest of landscapes, my sister’s face watching me. She smiles, I smile. I smile, she smiles. She gives me a quick slap, I cry, she smiles, I smi…
Shortly after three-o’clock on 28th July 2017, in a private room of a specialised hospice in suburban London, staffdisconnected the breathing machine that was keeping alive 11-month old infant, Charlie Gard. Lying on either side of him, his parents Connie Yates and Chris Gard held his hands, leaned close, and talked to him. They spoke to him of how proud they were of him. They saw him open hi…
For more than 20 years I have practiced nursing, first in oncology services, then in palliative care. As a teacher and psychotherapist for the past 10 years, I have had the opportunity to continue working with nursing students in palliative care and psychi-atric services, as well as to supervise nursing teams. An ethicist by training, I belong to an ethics committee in a neuropsychiatric hospit…
n March 2013, a group of detainees at Guantánamo Bay Detention Camp, Cuba, went on hunger strike. At the height of their protest, 106 individuals were refusing to eat. For detainees incarcerated for over a decade without charge or trial, food refusal offered a potent way to rebel. Having been stripped of their capacity for political communication and placed …
Doctor Who (1963–1989, 2005–) is a curiosity in the vast landscape of British tele- vision history. What started out as an educational children’s programme has transformed into a “pop-cultural artefact”1 and a “cultural phenomenon”.2 The Doctor, the eponymous hero of the BBC’s time travel programme, is a figure invested both with personal memori…
During World War II, advances in aviation became unmistakable. Many nations’ air forces entered the war flying biplane aircraft that were not much different from their predecessors of the previous world war. They were soon eclipsed by aircraft that took advantage of new designs that utilized many aeronautical advances of the interwar period such as new powerplants, stressed-skin aluminum stru…
One of the difficulties in the establishment of nature-study has been that there is no field for the work. This is no longer true. There is an awakening throughout the country. 1. Summer Camps need Nature Counsellors. It is admitted that nature lore is the most important and the most difficult position to fill in the summer camp. There are over 5000 camps. 2. Scouting and Camp Fire Organiz…
NASA engineers at Marshall Space Flight Center, along with their partners at other NASA centers and in private industry, are designing and building the next generation of rockets and spacecraft to transport cargo, equipment, and human explorers to space. Known collectively as Deep Space Exploration Systems, the Space Launch System (SLS) rocket, the Orion spacecraft, and ground systems at Kenned…
This emotional statement describes the long-distance ‘homecoming’ experi-ence of a young volunteer, a third-generation Armenian American from theBoston area, who arrived in Yerevan at the Zvartnots International Airport inJune 2007 to ‘discover’ his ‘ancestral homeland’ and to ‘move mountains’ inmodernArmenia.Thiswasnotajourneyalongapilgrimagetour.However,theperception of encoun…
In 1745, the Shengjing military governor (jiangjun), Daldangga, wrote to the Qian-long emperor (r. 1736–95) to propose building a guard post at the mouth of the Yalu (K. Amnok) River. The suggested place was Mangniushao, a sandbank located where the confluence of two tributaries of the Yalu River, the Caohe and the Aihe, flowed into the mainstream of the Yalu. These tri…
Botanical and scientific illustration share many common themes - the meticulous observation, the crucial composition, the precision of rendering and the accuracy of colour are all intrinsic to this niche genre of art. In this beautiful book, Sarah Jane Humphrey explains the techniques of the botanical artist but also introduces ideas for scientific illustration, so that the illustrator has a fu…
“There was no such thing as the Scientific Revolution, and this is a book about it” (Shapin 1996, 1). So began Stephen Shapin’s The Scientific Revolution, a work, con-cise and smart, that embodied an approach to the history of science termed “the social construction of science.” Shapin argued that if we are going to talk about a “scientific revolution,” then we need to see it not …
Water resources are indispensable for social development. Human needs shapedrivers and river basins, leading to a drastic modification of the global water cycle.Changes due to human activities are so large nowadays that they override naturalprocesses, leading to the end of a geological era and the beginning of a new onecalled“the Anthropocene”first conceptualized by Crutzen [1, 2]. Using th…
Bekisar adalah unggas elok hasil kawin silang antara ayam hutan dan ayam biasa yang sering menjadi hiasan rumah orang-orang kaya. Dan, adalah Lasi, anak desa yang berayah bekas serdadu Jepang yang memiliki kecantikan khas - kulit putih, mata eksotis - membawa dirinya menjadi bekisar di kehidupan megah seorang lelaki kaya di Jakarta, melalui bisnis berahi kalangan atas yang tak disadarinya. Las…
s the minister responsible for the local police, Lanskoi had particular grounds for concern over their poor performance. His, however, was not the only ministry dependent on the police. A contemporary journalist described the local police as, in effect, the eyes, ears, and hands of the state. “Almost everything discussed by ministerial departments,” he noted, “or…
Policing is one of those defining concepts of modernity about which much haswritten—to the point where it is difficult to imagine that there is much left to besaid—that is, at the same time, decisively modern. The modern conceptualizationof police referring to a fixed and commonly identifiable role, occupation andorganization, rather than simply a practice performed by the state through its…
Police, as the most visible arm of government and the primary interface between a state and its population, signify and implement a state’s right to engage in actions intended to ensure legislated acceptable behaviours from its populace (Dunham & Alpert, 2010; Pollock, 1998). The power and authority assigned to state police place police and acts…
Aku insinyur. Aku tak bisa menguraikan dengan baik hubungan antara kejujuran dan kesungguhan dalam pembangunan proyek ini dengan keberpihakan kepada masyarakat miskin. Apakah yang pertama merupakan manifestasi yang kedua? Apakah kejujuran dan kesungguhan sejatinya adalah perkara biasa bagi masyarakat berbudaya, dan harus dipilih karena keduanya merupakan hal yang niscaya untuk menghasilkan kema…
Manuscripts originate from literacy practices embedded in numerous social domains, such as education, administration, religion and trade. Expressed in spoken and written languages, various social activities prompt the development of organising principles and structures, which in turn serve as models for the agents and participants of literacy practices. The…
In what follows I discuss unreadability and its relation to reading and interpretation of experimental literature. What precisely does unread-ability mean? Where can it be located? How far does it impede reading and can it be overcome? I want to address these questions within the frameworks of narratology and literary pragmatics, and suggest that in som…
Grass seeds include the coleoptile (shoot sheath), the scutellum, the radicula and the coleorrhiza (root sheath) (Figure1.1). The scutellum is homologous to the leaf lamina of the cotyledon and the coleoptile to the leaf sheath of the cotyledon. Co-leoptile and coleorrhiza are membranes that protect shoot and leaf meristems and the radicula, respectively, during the first step of the germinatio…
In 2019, Juha Marttila, the President of the Central Union of Agricultural Pro-ducers and Forest Owners (MTK) in Finland, expressed his astonishment in apress interview about the increasing public criticism of intensive meat and dairyproduction:“The cow has kept us alive for some ten thousand years, so how comeit has now been made a criminal?”1He was quite right about the long interrela-tio…
This pioneering study of the fate of Buddhism during the communist period in Cambodia puts a human face on a dark period in Cambodia’s history. It is the first sustained analysis of the widely held assumption that the Khmer Rouge under Pol Pot had a centralized plan to liquidate the entire monastic order. Based on a thorough analysis of interview transcripts and a large body of contemporary m…
Love as a feeling is universal. Since we all have a sense for what it means, this default understanding of love is as deeply rooted and unconsciously ingrained in us as our relationship to our own family. Consequently, we are too familiar with it to be able to step back and really observe its form and significance. To really see what love is would require us to step outside of ourse…
"I come from a country that was created at midnight. When I almost died it was just after midday." When the Taliban took control of the Swat Valley in Pakistan, one girl spoke out. Malala Yousafzai refused to be silenced and fought for her right to an education. On Tuesday, October 9, 2012, when she was fifteen, she almost paid the ultimate price. She was shot in the head at point-blank r…
Each year I bring students from Harvard University to a Camphill community—usually, either Camphill Village USA in Copake, New York, or Heartbeet Lifesharing in Vermont. At Camphill my students encounter a social world that is different from their own. We travel from the busy streets of Cambridge to dirt roads and mountain valleys, where our passage may be bl…
Across North and South America, Indigenous people play a dual political role, building self-governing structures in their own nations and participating in the elections of settler states. Doing Democracy Differently asks how states are responding to demands for Indigenous representation and autonomy and in what ways the ongoing project of decolonization may unsettle the practice of democracy. B…
Islamic peoples account for one fifth of the world's population and yet there is widespread misunderstanding in the West of what Islam really is. Francis Robinson and his team set out to address this, revealing the complex and sometimes contrary nature of Muslim culture. As well as taking on the issues uppermost in everyone's minds, such as the role of religious and political fundamentalism, th…
This book is one of a series of 11 titles. Nine are monographs devoted to specific field sites (including this one) in Brazil, Chile, China, England, India, Italy, Trinidad and Turkey – they will be published in 2016–17. The series also includes a comparative book about all of our findings, published to accompany this title, and a book which contrasts the visu-als …